Chemistry

Affiliated Faculty Information

I. Affiliated Faculty, Lerner Research Institute, Cleveland Clinic

 
Ashok Agarwal, Ph.D. https://my.clevelandclinic.org/departments/urology-kidney/depts/reproductive-medicine Biological markers of oxidative stress; proteomic and bioinformatics in DNA damage, apoptosis and preserving fertility in patients with cancer; laboratory and clinical studies assessing efficacy of certain antioxidants in improving male fertility
Alex Almassan, Ph.D. http://www.lerner.ccf.org/cancerbio/almasan/  Autophagy; apoptosis; cell cycle; DNA damage; ubiquitin; DNA repair; cancer therapeutics; radiation therapy; leukemia; epithelial tumors; prostate cancer
Suneel Apte, M.B.B.S, Ph.D.  https://www.lerner.ccf.org/bme/apte/  Extracellular matrix; proteolysis; metalloproteinases; ADAMTS proteases; ADAMTS-like proteins; proteomics; morphogenesis; cardiovascular; musculoskeletal; birth defects; fetal-maternal medicine; eye disorders; neural tube; craniofacial development; smooth muscle; post-translational modification; inherited connective tissue disorders; osteoarthritis; primary cilium
Mark Aronica, M.D. https://www.lerner.ccf.org/immuno/aronica/  Mechanisms by which specific ECM proteins contribute to the onset of asthma
Kathleen Berkner, Ph.D. https://www.lerner.ccf.org/cms/berkner/  Vitamin K; vitamin K-dependent protein carboxylation; hemostasis; anticoagulation; calcification; vitamin K-dependent clotting factors deficiency (VKCFD); pseudoxanthoma elasticum; warfarin resistance; gamma-glutamyl carboxylase; vitamin K oxidoreductase (VKOR)
Mark Brown, Ph.D.  http://www.lerner.ccf.org/cms/brown/  Lipid metabolism; lipoprotein metabolism; atherosclerosis; obesity; diabetes; reverse cholesterol transport; triacylglycerol; nutrition
Tatiana Byzova, Ph.D.  https://www.lerner.ccf.org/neurosci/byzova/  Angiogenesis; endothelial cells; integrins; extracellular matrix; cell adhesion; tumor progression; vascular biology; signal transduction in endothelium and platelets; oxidative stress and vasculature; toll-like receptors in angiogenesis
John Crabb, Ph.D.  http://www.lerner.ccf.org/eye/crabb/  Eye; age-related macular degeneration; glaucoma; uveal melanoma; proteomics
Donna Driscoll, Ph.D.  https://www.lerner.ccf.org/cms/driscoll/  RNA biology; mRNA translational control; nutritional regulation of gene expression; selenium
Serpil Erzurum, M.D.  https://www.lerner.ccf.org/immuno/erzurum/  Asthma; pulmonary vascular disease; hypoxia; metabolism
Paul Fox, Ph.D.  https://www.lerner.ccf.org/cms/fox/  Angiogenesis; atherosclerosis; cell migration; endothelial cells; iron metabolism; macrophages; translational control
Vincent Hascall, Ph.D.  https://www.lerner.ccf.org/bme/hascall/  Hyaluronan in inflammation; asthma; diabetes; autophagy; hyperglycemia; connective tissue biology
Stanley Hazen, M.D., Ph.D.  https://www.lerner.ccf.org/cms/hazen/  Inflammation; atherosclerosis; asthma; myeloperoxidase; cardiovascular diseases; HDL; peroxidases; airway remodeling; intestinal microbiota; gut flora; cardiometabolic disease
Christopher Hine, Ph.D.  https://www.lerner.ccf.org/cms/hine/  Dietary restriction; aging; lifespan extension; stress resistance; exercise; hydrogen sulfide (H2S) production and metabolism; sulfur amino acid metabolism; endocrine signaling and longevity
Sadashiva Karnik, Ph.D.  http://www.lerner.ccf.org/cms/karnik/  GPCRs; angiotensin receptors; ARBs; biased signaling; cardiac hypertrophy; hypertension; heart failure; structure-function of GPCRs; transmembrane signaling; microRNA; gene expression; chromatin protein modifications; STAT3 and U-STAT3 signaling; RGS proteins
Xiaoxia Li, Ph.D.  https://www.lerner.ccf.org/immuno/li/  Signal transduction in innate and adaptive immunity
Daniel Lindner, M.D., Ph.D.  https://my.clevelandclinic.org/staff/3044-daniel-lindner  Mechanisms of acquired drug resistance in renal cancer, development of more effective drugs to treat myelodysplastic syndrome and acute myelogenous leukemia
Thomas McIntyre, Ph.D.  http://www.lerner.ccf.org/cellbio/mcintyre/  Lipid mediators; inflammatory signaling; platelet biology; biochemistry; acute kidney injury
Richard Padgett, Ph.D.  http://www.lerner.ccf.org/cms/padgett/  Transcription; RNA processing; RNA splicing; splicing factors; relation to cancer and developmental diseases; gene structure and function; genomics; evolution of genomes; RNA biochemistry
Edward Plow, Ph.D.  https://www.lerner.ccf.org/cms/plow/  Integrins; plasminogen; kindlins; thrombospondins; atherothrombosis
Eugene Podrez, M.D., Ph.D.  http://www.lerner.ccf.org/cms/podrez/  Atherosclerosis; thrombosis; atherothrombosis; platelets; macrophage; scavenger receptors; LDL; HDL; cholesterol; phospholipids; oxidative stress; lipid peroxidation
Jun Qin, Ph.D.  https://www.lerner.ccf.org/cms/qin/  Signal transduction; integrin; cell adhesion; cell migration; kinase; heart disease; cancer; structural biology; protein NMR; protein crystallography
Sujata Rao, Ph.D.  https://www.lerner.ccf.org/eye/rao/  Eye; developmental biology; circadian clock; neurovascular development; thyroid hormone signaling; cone photoreceptors; vascular remodeling
Nima Sharifi, M.D.  https://www.lerner.ccf.org/cancerbio/sharifi/  Prostate cancer; androgens; metabolism; steroids; castration-resistant prostate cancer; androgen receptor; hormone therapy; medical oncology; dihydrotestosterone; enzymes; biochemistry
Robert Silverman, Ph.D.  https://www.lerner.ccf.org/cancerbio/silverman/  Interferon; rnase l; antiviral innate immunity; oncolytic virotherapy, DNA methyltransferase inhibitor
Jonathan Smith, Ph.D.  https://www.lerner.ccf.org/cms/smith/  Atherosclerosis; HDL metabolism; atrial fibrillation; genetics; genomics; eQTL; gene expression; reverse cholesterol transport; dysfunctional HDL; RNAseq; allelic expression imbalance; ABCA1; mouse models; zinc finger nuclease
George Stark, Ph.D.  https://www.lerner.ccf.org/cancerbio/stark/  Interferons; IL-6; NFkB; STAT3; EGFR; drug resistance; DNA repair; lung cancer; breast cancer; prostate cancer; glioblastoma; septic shock
Dennis Stuehr, Ph.D.  http://www.lerner.ccf.org/immuno/stuehr/  Inflammation; nitric oxide; heme transport; soluble guanylate cyclase; electron transfer
Wai Hong Wilson Tang, M.D. http://www.lerner.ccf.org/cms/tang/  Heart failure; cardiomyopathy; nitrative stress; metabolomics; cardio-renal syndrome
Bruce Trapp, Ph.D.  http://www.lerner.ccf.org/neurosci/trapp/  Multiple sclerosis; glia; oligodendrocytes; astrocytes; neuroprotection; myelin, autism
Bin Zhang, Ph.D.  https://www.lerner.ccf.org/gmi/zhang/  Mechanism of intracellular trafficking in human disease development; protein secretion; endoplasmic reticulum stress; hemophilia; alpha-1-antitrypsin deficiency, cardiovascular diseases; cancer

II. Affiliated Faculty, Doctoral Clinical Laboratory Scientists

A. Robert J. Tomsich Pathology & Laboratory Medicine Institute, Cleveland Clinic
my.clevelandclinic.org/departments/pathology
Edmund Z. Reineks, M.D., Ph.D., DABCC  https://my.clevelandclinic.org/staff/15151-edmunds-reineks   Point of care testing; quality; lab directorship; special topics
Adam McShane, Ph.D., DABCC  https://my.clevelandclinic.org/staff/22478-adam-mcshane  Automated chemistry; cardiovascular disease; blood gases
Marvin Natowicz, M.D., Ph.D.  https://my.clevelandclinic.org/staff/4098-marvin-natowicz   Biochemical genetics; metabolic diseases
Manjula Gupta, Ph.D.   https://my.clevelandclinic.org/staff/823-manjula-gupta  Cancer; endocrinology
Jessica Colon-Franco, Ph.D., DABCC   https://my.clevelandclinic.org/staff/24086-jessica-colon-franco  Endocrinology; special chemistry; leadership
Kamran Kadkhoda, Ph.D., DABMLI    https://my.clevelandclinic.org/staff/24007-kamran-kadkhoda  Immunopathology; serology; allergy; cellular immunology
Grace Kroner, Ph.D. https://my.clevelandclinic.org/staff/26703-grace-kroner  Special chemistry; diabetes testing; laboratory test utilization; data analytics
B. Department of Pathology, Metrohealth Medical Center
www.metrohealth.org/pathology
Michael Ip, Ph.D., DABCC   Clinical chemistry; endocrinology; prenatal diagnosis; infertility; POCT; clinical toxicology; critical care lab; rapid response labs
C. Department of Pathology and Laboratory Medicine, Children's Hospital Medical Center of Akron
www.akronchildrens.org/locations/Pathology-and-Laboratory-Medicine.html
Sihe Wang, Ph.D., DABCC   https://www.akronchildrens.org/people/Sihe-Wang.html  General clinical chemistry; pediatric testing; chromatography; mass spectrometry; assay development; CLIA regulation; laboratory management; process improvement
D. Quest Diagnostics Cleveland Hearthlab Center of Excellence 
www.clevelandheartlab.com
Deborah Sun, Ph.D.   Clinical laboratory operations and management

III. Affiliated Faculty Case Western Reserved University or MetroHealth/Case Western Reserve University

*Faculty with Primary position at MetroHealth Medical Center
Romani Andrea M.D., Ph.D.  https://physiology.case.edu/people/faculty/andrea-romani/   Regulation of magnesium homeostasis and transport in mammalian cells
Ge Jin, Ph.D.  https://case.edu/dental/node/2466   Mechanism of cancer cell-derived cytokines and/or metabolites; immune response and role of HIV-infection in development/progression of non-AIDS-defining cancers
*Jeffrey Schelling, M.D. (MetroHealth Medical Center/Case Western Reserve University)  https://physiology.case.edu/people/visitor/jeffrey-r-schelling/  Mechanisms of chronic kidney disease progression; in vitro molecular and cellular methods, animal models and human studies investigating glomerular and tubulointerstitial pathophysiology
*Bing-Cheng Wang, Ph.D.  (MetroHealth Medical Center/Case Western Reserve University) https://case.edu/medicine/pharmacology/people/bingcheng-wang  Roles of Eph receptor tyrosine kinases in invasive growth and distal metastasis of cancer cells
Wen-Quan Zou, M.D., Ph.D.  https://case.edu/medicine/pathology/faculty/wen-quan-zou   Protein aggregation in the conformational diseases; pathologic prion proteins (PrPC and PrPSc) in prion diseases (PrD); neurotoxic amyloid β (Aβ) in Alzheimer disease (AD); Creutzfeldt-Jakob disease (CJD)

IV. Affiliated Faculty, Cleveland State University

Jamila Hirbawi, Ph.D. Manager, Freshman Chemistry Program, Department of Chemistry

V. Affiliated Faculty, NASA

James L. Smialek Ph.D. https://www.linkedin.com High-temperature oxidation; coatings