List of Regular and Adjunct Faculty

List of Regular and Adjunct Faculty 
Name Descriptors Research Interests
Ashok Agarwal, Ph.D.
CCF Biological markers of oxidative stress; proteomic and bioinformatics in DNA damage, apoptosis, and preserving fertility in patients with cancer; laboratory and clinical studies assessing the efficacy of certain antioxidants in improving male fertility
David Anderson, Ph.D.
CSU Novel HPLC-MS techniques to measure biological compounds in diagnosis/treatment and in understanding disease - include proteins, peptides, gangliosides, and drugs. Developed gradient chromatofocusing technique in the separation of proteins by pH gradients on ion-exchange columns. Research in chromatographic theory involving fundamental parameters of mobile phase and compounds chromatographed predicting separation.  
Romani Andrea M.D., Ph.D.
CWRU Regulation of magnesium homeostasis and transport in mammalian cells
Suneel Apte, M.B.B.S, Ph.D. CCF Extracellular matrix; proteolysis; metalloproteinases; ADAMTS proteases; ADAMTS-like proteins; proteomics; morphogenesis; cardiovascular; musculoskeletal; birth defects; fetal-maternal medicine; eye disorders; neural tube; craniofacial development; smooth muscle; post-translational modification; inherited connective tissue disorders; osteoarthritis; primary cilium
Mark Aronica, M.D. CCF Mechanisms by which specific ECM proteins contribute to the onset of asthma
Mekki Bayachou, Ph.D. CSU Functional biomaterials; antithrombotic surfaces; electron-transfer; nitric oxide synthases; metalloproteins; metalloenzymes; cyt P450s; bio-electrochemistry; DNA-sensors; DNA-protein interaction; small molecule metabolite sensors; nanotechnology
Anthony Berdis, Ph.D. CSU The Berdis lab is developing novel diagnostic and therapeutic agents against several types of cancers including glioblastoma multiforme, breast, pancreatic, and various leukemias.  His research involves developing artificial nucleosides that increase the efficacy of existing anti-cancer agents with the goal of effectively kill cancer cells while leaving normal cells unaffected. 
Kathleen Berkner, Ph.D. CCF Vitamin K; vitamin K-dependent protein carboxylation; hemostasis; anticoagulation; calcification; vitamin K-dependent clotting factors deficiency (VKCFD); pseudoxanthoma elasticum; warfarin resistance; gamma-glutamyl carboxylase; vitamin K oxidoreductase (VKOR)
Warren Boyd, Ph.D. CSU Coordination chemistry of azodioxides, transition metal-catalyzed organic reactions, and metal-based anticancer agents.
Mark Brown, Ph.D. CCF Lipid metabolism; lipoprotein metabolism; atherosclerosis; obesity; diabetes; reverse cholesterol transport; triacylglycerol; nutrition
Tatiana Byzova, Ph.D. CCF Angiogenesis; endothelial cells; integrins; extracellular matrix; cell adhesion; tumor progression; vascular biology; signal transduction in endothelium and platelets; oxidative stress and vasculature; toll-like receptors in angiogenesis
Jessica Colon-Franco, Ph.D., DABCC CCF Endocrinology; special chemistry; leadership
Donna Driscoll, Ph.D. CCF RNA biology; mRNA translational control; nutritional regulation of gene expression; selenium
Serpil Erzurum, M.D. CCF Asthma; pulmonary vascular disease; hypoxia; metabolism
Valentin Gogonea, Ph.D. CSU Computational chemistry; enzyme reactivity; nitric oxide synthase; hydrogenase; cholesterol transport; deuterium exchange; quantum mechanical molecular mechanics; molecular dynamics; protein folding
Junior Gonzales, Ph.D. CSU Developing quantitative tools to sense/measure (via the use of re-engineered bio-tropical peptides) neuropathies, cancer, and tropical infectious diseases. We endure our research by targeting sodium-channels that are expressed and/or involved in the formation of these unmet medical dysfunctions.
Baochuan Guo, Ph.D. CSU Focus on the development of mass spectrometric-based technologies for qualitative and quantitative analysis of various biomolecules ranging from small drug molecules to large proteins as well as application of the technologies developed for medical use.
Stanley Hazen, M.D., Ph.D. CCF Inflammation; atherosclerosis; asthma; myeloperoxidase; cardiovascular diseases; HDL; peroxidases; airway remodeling; intestinal microbiota; gut flora; cardiometabolic disease
Christopher Hine, Ph.D. CCF Dietary restriction; aging; lifespan extension; stress resistance; exercise; hydrogen sulfide (H2S) production and metabolism; sulfur amino acid metabolism; endocrine signaling and longevity
Ge Jin, Ph.D. Metro Health  CWRU Mechanism of cancer cell-derived cytokines and/or metabolites; immune response and role of HIV-infection in development/progression of non-AIDS-defining cancers
Kamran Kadkhoda, Ph.D., DABMLI CCF Immunopathology; serology; allergy; cellular immunology
Michael Kalafatis, Ph.D. CSU

Blood Coagulation and Thrombosis. Thrombosis is the primary cause of death worldwide and one of two major focuses of my research. My laboratory has a great deal of expertise in the biochemistry of coagulation
Cancer and Apoptosis. Cancer is the second cause of death worldwide. The traditional way to treat cancer today is “cut, poison, and burn” which correlates to surgery, chemotherapy, and radiation respectively with the known devastating side effects. My laboratory is striving to establish a treatment for cancer that uses natural non-toxic substances.

Sadashiva Karnik, Ph.D. CCF GPCRs; angiotensin receptors; ARBs; biased signaling; cardiac hypertrophy; hypertension; heart failure; structure-function of GPCRs; transmembrane signaling; microRNA; gene expression; chromatin protein modifications; STAT3 and U-STAT3 signaling; RGS proteins
Grace Kroner, Ph.D. CCF Special chemistry; diabetes testing; laboratory test utilization; data analytics
Xiaoxia Li, Ph.D. CCF Signal transduction in innate and adaptive immunity
Daniel Lindner, M.D., Ph.D. CCF Mechanisms of acquired drug resistance in renal cancer, development of more effective drugs to treat myelodysplastic syndrome and acute myelogenous leukemia
Thomas McIntyre, Ph.D. CCF Lipid mediators; inflammatory signaling; platelet biology; biochemistry; acute kidney injury
Adam McShane, Ph.D., DABCC CCF Automated chemistry; cardiovascular disease; blood gases
Marvin Natowicz, M.D., Ph.D. CCF Biochemical genetics; metabolic diseases
Richard Padgett, Ph.D. CCF Transcription; RNA processing; RNA splicing; splicing factors; relation to cancer and developmental diseases; gene structure and function; genomics; evolution of genomes; RNA biochemistry
Eugene Podrez, M.D., Ph.D. CCF Atherosclerosis; thrombosis; atherothrombosis; platelets; macrophage; scavenger receptors; LDL; HDL; cholesterol; phospholipids; oxidative stress; lipid peroxidation
Jun Qin, Ph.D. CCF Signal transduction; integrin; cell adhesion; cell migration; kinase; heart disease; cancer; structural biology; protein NMR; protein crystallography
Sujata Rao, Ph.D. CCF Eye; developmental biology; circadian clock; neurovascular development; thyroid hormone signaling; cone photoreceptors; vascular remodeling
Edmund Z. Reineks, M.D., Ph.D., DABCC CCF Point of care testing; quality; lab directorship; special topics
Ali A Rownaghi, Ph.D. CSU The primary focus (Catalysis and Membrane Laboratory) is on creating, understanding, and rationally engineering advanced materials for energy and environmental applications through innovative and scalable processing strategies
Jeffrey Schelling, M.D. Metro Health CWRU Mechanisms of chronic kidney disease progression; in vitro molecular and cellular methods, animal models, and human studies investigating glomerular and tubulointerstitial pathophysiology
Nima Sharifi, M.D. CCF Prostate cancer; androgens; metabolism; steroids; castration-resistant prostate cancer; androgen receptor; hormone therapy; medical oncology; dihydrotestosterone; enzymes; biochemistry
Robert Silverman, Ph.D CCF Interferon; rnase l; antiviral innate immunity; oncolytic virotherapy, DNA methyltransferase inhibitor
James L. Smialek Ph.D. NASA High-temperature oxidation; coatings
Jonathan Smith, Ph.D. CCF Atherosclerosis; HDL metabolism; atrial fibrillation; genetics; genomics; eQTL; gene expression; reverse cholesterol transport; dysfunctional HDL; RNAseq; allelic expression imbalance; ABCA1; mouse models; zinc finger nuclease
George Stark, Ph.D. CCF Interferons; IL-6; NFkB; STAT3; EGFR; drug resistance; DNA repair; lung cancer; breast cancer; prostate cancer; glioblastoma; septic shock
Dennis Stuehr, Ph.D. CCF Inflammation; nitric oxide; heme transport; soluble guanylate cyclase; electron transfer
Bin Su, Ph.D. CSU Drug development, Cancer pharmacology, Endocrinology, African trypanosomiasis, Synthetic medicinal chemistry, Pharmacokinetic study
Xue-Long Sun, Ph.D. CSU

 * Glycan-based antiviral and anti-inflammation drug development, immunomodulation, targeted drug delivery, nanomaterial, and biosensor applications.
  * Biomimetic synthesis of native anticoagulant biomolecules for compensation of their loss in the pathological site as an on-demand therapeutic strategy.
  * Profiling and modulating cell surface glycosylation pattern and cell function.

Wai Hong Wilson Tang, M.D. CCF Heart failure; cardiomyopathy; nitrative stress; metabolomics; cardio-renal syndrome
Bruce Trapp, Ph.D. CCF Multiple sclerosis; glia; oligodendrocytes; astrocytes; neuroprotection; myelin, autism
John F Turner, Ph.D. CSU Raman spectroscopy; fluorescence; infrared; IR; near infrared; NIR; visible; chemical imaging; multivariate analysis; chemometrics; mineral; biomineral; bone; teeth; biomaterials; implant materials; bioanalysis; spectral imaging; hyperspectral imaging; multispectral imaging; liquid crystal tunable filter; LCTF; acousto-optic tunable filter; AOTF; CCD; charge coupled device, spectroscopy; gemology; gemstone; miner- alogy; geology; Raman database; poly-llactide
Bing-Cheng Wang, Ph.D. Metro Health CWRU Roles of Eph receptor tyrosine kinases in invasive growth and distal metastasis of cancer cells
Yan Xu, Ph.D. CSU Clinical and preclinical pharmacokinetics; analytical method development for drugs and metabolites; lipidomic profiling and quantitation of biomarkers of human diseases; metabolic flux analysis of biochemical pathways; metabolomics of multicomponent formulations; mass spectrometry; liquid and gas chromatography; enzyme immunoassay; capillary electrophoresis; electroanalytical techniques
Bin Zhang, Ph.D. CCF Mechanism of intracellular trafficking in human disease development; protein secretion; endoplasmic reticulum stress; hemophilia; alpha-1-antitrypsin deficiency, cardiovascular diseases; cancer
Aimin Zhou, Ph.D. CSU Investigating the role of RNase L, a key enzyme in interferon action against viral infection and cell proliferation, in immune cell functions and the pathogenesis of inflammatory diseases such as diabetes, non-alcohol fatty liver disease, and acute kidney injury by using cell and animal models. 
Wen-Quan Zou, M.D., Ph.D. CWRU Protein aggregation in the conformational diseases; pathologic prion proteins (PrPC and PrPSc) in prion diseases (PrD); neurotoxic amyloid β (Aβ) in Alzheimer disease (AD); Creutzfeldt-Jakob disease (CJD