List of Regular and Adjunct Faculty
| Name | Descriptors | Research Interests |
| Ashok Agarwal, Ph.D. |
CCF | Biological markers of oxidative stress; proteomic and bioinformatics in DNA damage, apoptosis, and preserving fertility in patients with cancer; laboratory and clinical studies assessing the efficacy of certain antioxidants in improving male fertility |
| David Anderson, Ph.D. |
CSU | Novel HPLC-MS techniques to measure biological compounds in diagnosis/treatment and in understanding disease - include proteins, peptides, gangliosides, and drugs. Developed gradient chromatofocusing technique in the separation of proteins by pH gradients on ion-exchange columns. Research in chromatographic theory involving fundamental parameters of mobile phase and compounds chromatographed predicting separation. |
| Romani Andrea M.D., Ph.D. |
CWRU | Regulation of magnesium homeostasis and transport in mammalian cells |
| Suneel Apte, M.B.B.S, Ph.D. | CCF | Extracellular matrix; proteolysis; metalloproteinases; ADAMTS proteases; ADAMTS-like proteins; proteomics; morphogenesis; cardiovascular; musculoskeletal; birth defects; fetal-maternal medicine; eye disorders; neural tube; craniofacial development; smooth muscle; post-translational modification; inherited connective tissue disorders; osteoarthritis; primary cilium |
| Mark Aronica, M.D. | CCF | Mechanisms by which specific ECM proteins contribute to the onset of asthma |
| Mekki Bayachou, Ph.D. | CSU | Functional biomaterials; antithrombotic surfaces; electron-transfer; nitric oxide synthases; metalloproteins; metalloenzymes; cyt P450s; bio-electrochemistry; DNA-sensors; DNA-protein interaction; small molecule metabolite sensors; nanotechnology |
| Anthony Berdis, Ph.D. | CSU | The Berdis lab is developing novel diagnostic and therapeutic agents against several types of cancers including glioblastoma multiforme, breast, pancreatic, and various leukemias. His research involves developing artificial nucleosides that increase the efficacy of existing anti-cancer agents with the goal of effectively kill cancer cells while leaving normal cells unaffected. |
| Kathleen Berkner, Ph.D. | CCF | Vitamin K; vitamin K-dependent protein carboxylation; hemostasis; anticoagulation; calcification; vitamin K-dependent clotting factors deficiency (VKCFD); pseudoxanthoma elasticum; warfarin resistance; gamma-glutamyl carboxylase; vitamin K oxidoreductase (VKOR) |
| Warren Boyd, Ph.D. | CSU | Coordination chemistry of azodioxides, transition metal-catalyzed organic reactions, and metal-based anticancer agents. |
| Mark Brown, Ph.D. | CCF | Lipid metabolism; lipoprotein metabolism; atherosclerosis; obesity; diabetes; reverse cholesterol transport; triacylglycerol; nutrition |
| Tatiana Byzova, Ph.D. | CCF | Angiogenesis; endothelial cells; integrins; extracellular matrix; cell adhesion; tumor progression; vascular biology; signal transduction in endothelium and platelets; oxidative stress and vasculature; toll-like receptors in angiogenesis |
| Jessica Colon-Franco, Ph.D., DABCC | CCF | Endocrinology; special chemistry; leadership |
| Donna Driscoll, Ph.D. | CCF | RNA biology; mRNA translational control; nutritional regulation of gene expression; selenium |
| Serpil Erzurum, M.D. | CCF | Asthma; pulmonary vascular disease; hypoxia; metabolism |
| Valentin Gogonea, Ph.D. | CSU | Computational chemistry; enzyme reactivity; nitric oxide synthase; hydrogenase; cholesterol transport; deuterium exchange; quantum mechanical molecular mechanics; molecular dynamics; protein folding |
| Junior Gonzales, Ph.D. | CSU | Developing quantitative tools to sense/measure (via the use of re-engineered bio-tropical peptides) neuropathies, cancer, and tropical infectious diseases. We endure our research by targeting sodium-channels that are expressed and/or involved in the formation of these unmet medical dysfunctions. https://www.gonzalesarevalo-lab.com/about |
| Baochuan Guo, Ph.D. | CSU | Focus on the development of mass spectrometric-based technologies for qualitative and quantitative analysis of various biomolecules ranging from small drug molecules to large proteins as well as application of the technologies developed for medical use. |
| Stanley Hazen, M.D., Ph.D. | CCF | Inflammation; atherosclerosis; asthma; myeloperoxidase; cardiovascular diseases; HDL; peroxidases; airway remodeling; intestinal microbiota; gut flora; cardiometabolic disease |
| Christopher Hine, Ph.D. | CCF | Dietary restriction; aging; lifespan extension; stress resistance; exercise; hydrogen sulfide (H2S) production and metabolism; sulfur amino acid metabolism; endocrine signaling and longevity |
| Ge Jin, Ph.D. | Metro Health CWRU | Mechanism of cancer cell-derived cytokines and/or metabolites; immune response and role of HIV-infection in development/progression of non-AIDS-defining cancers |
| Kamran Kadkhoda, Ph.D., DABMLI | CCF | Immunopathology; serology; allergy; cellular immunology |
| Michael Kalafatis, Ph.D. | CSU |
Blood Coagulation and Thrombosis. Thrombosis is the primary cause of death worldwide and one of two major focuses of my research. My laboratory has a great deal of expertise in the biochemistry of coagulation |
| Sadashiva Karnik, Ph.D. | CCF | GPCRs; angiotensin receptors; ARBs; biased signaling; cardiac hypertrophy; hypertension; heart failure; structure-function of GPCRs; transmembrane signaling; microRNA; gene expression; chromatin protein modifications; STAT3 and U-STAT3 signaling; RGS proteins |
| Grace Kroner, Ph.D. | CCF | Special chemistry; diabetes testing; laboratory test utilization; data analytics |
| Xiaoxia Li, Ph.D. | CCF | Signal transduction in innate and adaptive immunity |
| Daniel Lindner, M.D., Ph.D. | CCF | Mechanisms of acquired drug resistance in renal cancer, development of more effective drugs to treat myelodysplastic syndrome and acute myelogenous leukemia |
| Thomas McIntyre, Ph.D. | CCF | Lipid mediators; inflammatory signaling; platelet biology; biochemistry; acute kidney injury |
| Adam McShane, Ph.D., DABCC | CCF | Automated chemistry; cardiovascular disease; blood gases |
| Marvin Natowicz, M.D., Ph.D. | CCF | Biochemical genetics; metabolic diseases |
| Richard Padgett, Ph.D. | CCF | Transcription; RNA processing; RNA splicing; splicing factors; relation to cancer and developmental diseases; gene structure and function; genomics; evolution of genomes; RNA biochemistry |
| Eugene Podrez, M.D., Ph.D. | CCF | Atherosclerosis; thrombosis; atherothrombosis; platelets; macrophage; scavenger receptors; LDL; HDL; cholesterol; phospholipids; oxidative stress; lipid peroxidation |
| Jun Qin, Ph.D. | CCF | Signal transduction; integrin; cell adhesion; cell migration; kinase; heart disease; cancer; structural biology; protein NMR; protein crystallography |
| Sujata Rao, Ph.D. | CCF | Eye; developmental biology; circadian clock; neurovascular development; thyroid hormone signaling; cone photoreceptors; vascular remodeling |
| Edmund Z. Reineks, M.D., Ph.D., DABCC | CCF | Point of care testing; quality; lab directorship; special topics |
| Ali A Rownaghi, Ph.D. | CSU | The primary focus (Catalysis and Membrane Laboratory) is on creating, understanding, and rationally engineering advanced materials for energy and environmental applications through innovative and scalable processing strategies |
| Jeffrey Schelling, M.D. | Metro Health CWRU | Mechanisms of chronic kidney disease progression; in vitro molecular and cellular methods, animal models, and human studies investigating glomerular and tubulointerstitial pathophysiology |
| Nima Sharifi, M.D. | CCF | Prostate cancer; androgens; metabolism; steroids; castration-resistant prostate cancer; androgen receptor; hormone therapy; medical oncology; dihydrotestosterone; enzymes; biochemistry |
| Robert Silverman, Ph.D | CCF | Interferon; rnase l; antiviral innate immunity; oncolytic virotherapy, DNA methyltransferase inhibitor |
| James L. Smialek Ph.D. | NASA | High-temperature oxidation; coatings |
| Jonathan Smith, Ph.D. | CCF | Atherosclerosis; HDL metabolism; atrial fibrillation; genetics; genomics; eQTL; gene expression; reverse cholesterol transport; dysfunctional HDL; RNAseq; allelic expression imbalance; ABCA1; mouse models; zinc finger nuclease |
| George Stark, Ph.D. | CCF | Interferons; IL-6; NFkB; STAT3; EGFR; drug resistance; DNA repair; lung cancer; breast cancer; prostate cancer; glioblastoma; septic shock |
| Dennis Stuehr, Ph.D. | CCF | Inflammation; nitric oxide; heme transport; soluble guanylate cyclase; electron transfer |
| Bin Su, Ph.D. | CSU | Drug development, Cancer pharmacology, Endocrinology, African trypanosomiasis, Synthetic medicinal chemistry, Pharmacokinetic study |
| Xue-Long Sun, Ph.D. | CSU |
* Glycan-based antiviral and anti-inflammation drug development, immunomodulation, targeted drug delivery, nanomaterial, and biosensor applications. |
| Wai Hong Wilson Tang, M.D. | CCF | Heart failure; cardiomyopathy; nitrative stress; metabolomics; cardio-renal syndrome |
| Bruce Trapp, Ph.D. | CCF | Multiple sclerosis; glia; oligodendrocytes; astrocytes; neuroprotection; myelin, autism |
| John F Turner, Ph.D. | CSU | Raman spectroscopy; fluorescence; infrared; IR; near infrared; NIR; visible; chemical imaging; multivariate analysis; chemometrics; mineral; biomineral; bone; teeth; biomaterials; implant materials; bioanalysis; spectral imaging; hyperspectral imaging; multispectral imaging; liquid crystal tunable filter; LCTF; acousto-optic tunable filter; AOTF; CCD; charge coupled device, spectroscopy; gemology; gemstone; miner- alogy; geology; Raman database; poly-llactide |
| Bing-Cheng Wang, Ph.D. | Metro Health CWRU | Roles of Eph receptor tyrosine kinases in invasive growth and distal metastasis of cancer cells |
| Yan Xu, Ph.D. | CSU | Clinical and preclinical pharmacokinetics; analytical method development for drugs and metabolites; lipidomic profiling and quantitation of biomarkers of human diseases; metabolic flux analysis of biochemical pathways; metabolomics of multicomponent formulations; mass spectrometry; liquid and gas chromatography; enzyme immunoassay; capillary electrophoresis; electroanalytical techniques |
| Bin Zhang, Ph.D. | CCF | Mechanism of intracellular trafficking in human disease development; protein secretion; endoplasmic reticulum stress; hemophilia; alpha-1-antitrypsin deficiency, cardiovascular diseases; cancer |
| Aimin Zhou, Ph.D. | CSU | Investigating the role of RNase L, a key enzyme in interferon action against viral infection and cell proliferation, in immune cell functions and the pathogenesis of inflammatory diseases such as diabetes, non-alcohol fatty liver disease, and acute kidney injury by using cell and animal models. |
| Wen-Quan Zou, M.D., Ph.D. | CWRU | Protein aggregation in the conformational diseases; pathologic prion proteins (PrPC and PrPSc) in prion diseases (PrD); neurotoxic amyloid β (Aβ) in Alzheimer disease (AD); Creutzfeldt-Jakob disease (CJD |